Kufotokozera

Rosuvastatin Calcium (BANM, JAN, USAN) amadziwika kuti Rosuvastatin ku US.ndi mpikisano wa HMG-CoA reductase inhibitor wokhala ndi IC50 ya 11 nM[1].Rosuvastatin Calcium imatchinga mwamphamvu jini yokhudzana ndi ether-a-go-go (hERG) yomwe ili ndi IC50 ya 195 nM, kuchedwa kuyambiranso kwa mtima, ndipo potero kumatenga nthawi yayitali (APDs) ndikuwongolera kagawo ka QT (QTc)[2].Rosuvastatin Calcium imachepetsa kufotokozera kwa hERG yokhwima komanso kuyanjana kwa mapuloteni a kutentha kwa 70 (Hsp70) ndi mapuloteni a hERG.Rosuvastatin Calcium ndiyothandiza kwambiri potsitsa mafuta otsika a lipoprotein (LDL) cholesterol, triglycerides, ndi ma protein a C-reactive protein[3].

Zambiri pamisonkhano yamatchulidwe amankhwala: Mayina Osavomerezeka Padziko Lonse.

Chidziwitso chofunikira: Dongosolo lapadziko lonse la Drugs.com likutulutsidwa ndi BETA.Izi zikutanthauza kuti ikukonzedwabe ndipo ikhoza kukhala ndi zolakwika.Sichikupangidwa kuti chilowe m'malo mwa ukatswiri ndi chiweruzo cha dokotala wanu, wazamankhwala kapena katswiri wina wazachipatala.Siziyenera kutanthawuzidwa kusonyeza kuti kugwiritsa ntchito mankhwala aliwonse m'dziko lililonse ndikotetezeka, koyenera kapena kothandiza kwa inu.Funsani dokotala wanu musanamwe mankhwala aliwonse.

Ku US, Rosuvastatin (rosuvastatin systemic) ndi membala wa gulu lamankhwala la statins ndipo amagwiritsidwa ntchito pochiza Atherosclerosis, High Cholesterol, High Cholesterol - Familial Heterozygous, High Cholesterol - Homozygous Family, Hyperlipoproteinemia, Hyperlipoproteinemia Type IIa - Okwera LDL, Hyperlipoproteinemia IIb - Okwera LDL VLDL, Hyperlipoproteinemia Type III - Okwera beta-VLDL IDL, Hyperlipoproteinemia Type IV - VLDL yokwera, Hypertriglyceridemia ndi Kupewa Matenda a Mtima.

Mbiri

Choletsa chosankha, chopikisana cha HMG-CoA reductase, chomwenso ndi antilipidemic.

Kusungirako

Kapangidwe ka mankhwala