Doxycycline hyclate, yomwe imadziwika kuti doxycycline, ndi mankhwala omwe amagwiritsidwa ntchito kwambiri pofufuza zanyama. Palibe amene angangoweruza yemwe ali bwino pakati pa izo ndi fluphenazole.
Pamsika wazowona zanyama, imodzi mwamankhwala odziwika bwino a tetracycline antimicrobial ndi doxycycline, omwe ndi mankhwala odziwika bwino kwa alimi ndi madotolo anyama. Komabe, pharmacology ndi kugwiritsa ntchito kumafuna khama la akatswiri, kotero simungagwiritse ntchito bwino ngati mukungodziwa mankhwalawa. The antibacterial limagwirira wa doxycycline ndi kuti makamaka amalowa bakiteriya selo, Chili ndi ribosome 30S subunit chandamale, ndi organelle wa bakiteriya selo, motero inhibiting kaphatikizidwe wa mapuloteni bakiteriya, ndi kulola lokha kusewera ogwira antibacterial kwenikweni.
Ndi matenda ati omwe angachiritsidwe pogwiritsa ntchito doxycycline?
Doxycycline nthawi zambiri ntchito zochizira mycoplasma nkhuku ndi kupuma matenda nkhumba, makamaka osakaniza matenda a mycoplasma ndi mabakiteriya.
● Matenda a bakiteriya
Kwa odwala pleuropneumonia, chibayo cha nkhumba ndi matenda ena, amatha kugwiritsa ntchito doxycycline hydrochloride + fluphenazole + antipyretic mankhwala.
Kwa ma actinomycetes omwe angayambitse ma pustules omwe amatha kukula m'malo osiyanasiyana pa nkhumba, doxycycline hydrochloride nthawi zambiri imakhala ndi zotsatira zabwino.
● Matenda ofala m’thupi
Kwa mycoplasma, yomwe imadziwikanso kuti wheezing, doxycycline hydrochloride + flupenthixol ingagwiritsidwe ntchito.
Spirochetes (kamwazi wa nkhumba, etc.).
Doxycycline hydrochloride imakhala yogwira mtima kwambiri ikaperekedwa ku matenda monga magazi a protozoa, omwe nthawi zambiri timawatcha kuti epizootics.
Ma antimicrobial anayi akuluakulu a tetracycline
Pamsika wamakono wamankhwala a Chowona Zanyama, ma antimicrobial a tetracycline akuluakulu ndi doxycycline, tetracycline, oxytetracycline ndi chlortetracycline, omwe ali ndi kusiyana kwakukulu wina ndi mnzake. Ngati kulamula malinga tilinazo, doxycycline> tetracycline> chlortetracycline> oxytetracycline. Kodi mukudziwa chifukwa chake chidwi cha chlortetracycline chimakhala pafupi ndi oxytetracycline? M'malo mwake, maantibayotiki asanaletsedwe m'zakudya, chlortetracycline idagwiritsidwa ntchito kwambiri pazakudya zanyama, pamlingo wochepa, tsiku lililonse komanso kwa nthawi yayitali, monga momwe anthu amadyera ndi MSG.
Mlingo wochepa, kufalikira, komanso kudyetsa tsiku ndi tsiku kwa chlortetracycline kwathandiza kuti nyama zizichita bwino komanso zimalimbikitsa kukula kwachangu komanso kwathanzi kwaulimi, zomwe, komabe, zimabweretsanso vuto lalikulu, ndiko kuti, mlingo wotere, njira ndi njira kulima zambiri. osiyanasiyana bakiteriya kukana izo. Choncho, mankhwala amtunduwu akaletsedwa kugwiritsidwa ntchito m'zakudya, ndikupita patsogolo kwambiri pakuwongolera kugwiritsa ntchito mankhwala opha tizilombo toyambitsa matenda kuti asinthe mankhwalawa kukhala mankhwala omwe amayenera kuperekedwa ndi chowonadi. Akuti, pambuyo pa kugwiritsiridwa ntchito kovomerezeka kumeneku, pambuyo pa kubwezeretsedwa kwa chilengedwe kwa nthawi yaitali, kukhudzidwa kwake kungabwezeretsedwe m'tsogolomu.
Chifukwa chiyani doxycycline ndi yofunika?
Doxycycline hyclate ufa, imodzi mwa mankhwala ophera tizilombo toyambitsa matenda a tetracycline, yakhala yopambana kwambiri mu chipatala cha Chowona Zanyama kwa zaka zambiri kotero kuti yakhala yachiwiri yaikulu kwambiri pambuyo pa fluphenazole. Komanso, pankhani ya mankhwala a ziweto ndi nkhuku matenda kuti n'zovuta chitakonzedwa mu nthawi yochepa, monga sanali malungo, mpweya thumba mchere, fuluwenza, ndi mycoplasma bursa, etc., doxycycline nthawi zonse kusewera ake. wapadera achire udindo ogwira ntchito zachipatala za ziweto ndi nkhuku matenda. Kawirikawiri, mu chithandizo choperekedwa ndi veterinarians, kapena popanda kutenga nawo mbali kwa doxycycline, zotsatira zake nthawi zina zimakhala masewera a zero "othandiza" kapena "osagwira ntchito".
Kufunika kwa chithandizo chamankhwala cha doxycycline muzaulimi kwakula kwambiri m'zaka zingapo zapitazi chifukwa cha kuwonongeka kwa bursitis, matenda ovuta kuwongolera kupuma komanso makamaka mycoplasma bursa. Makamaka mycoplasma bursa, yomwe tsopano si nyengo konse, imapezeka kawirikawiri komanso kawirikawiri chaka chonse. Chifukwa chake, omwe amalabadira msika wa doxycycline apeza kuti kufunikira kwa msika wa doxycycline kwataya nyengo yake. Chifukwa chake, ngakhale dziko likadalowa m'chilimwe chotentha, kufunikira kwa msika wa doxycycline sikunatsike chifukwa cha kutentha kwambiri.
Ma antimicrobial spectrum adoxycycline hyclateimalola kuti ipeze zotsatira zabwino zochizira motsutsana ndi mabakiteriya a gram-positive, gram-negative, aerobic ndi anaerobic, komanso rickettsia, spirochetes, mycoplasma, chlamydia ndi protozoa, zomwe zimapangitsa kuti doxycycline izindikiridwe ndi alimi ndi veterinarians kwa ambiri. zaka. Komanso, mphamvu ya doxycycline pa mabakiteriya a gram-positive ndi yabwino kwambiri kuposa mabakiteriya a gram-negative, makamaka pamene mankhwala ambiri sali othandiza pa Staphylococcus, zotsatira za doxycycline nthawi zambiri zimakhala zokondweretsa.
Chotsatira chake, pakati pa mankhwala ophera tizilombo toyambitsa matenda a tetracycline, doxycycline sichingafanane ndi mabakiteriya ena otsutsana ndi mabakiteriya omwe amapezeka ku matenda opuma kupuma monga Staphylococcus, Streptococcus pyogenes ndi Pneumococcus, chomwe ndi chimodzi mwa zifukwa zofunika kwambiri zomwe mankhwala ambiri a Chowona Zanyama zochizira matenda opuma amatha. kukhala osiyana kwambiri ndi kapena popanda kuchitapo kanthu kwa doxycycline.
Zopereka zopangidwa ndi CPF
CPF, wotsogola wamankhwala ndiwopanga doxycyclinea APIs ndi kupangidwa komaliza ku China apeza kuti kwenikweni, ofufuza a labotale, omwe angakonde kufufuza zoona za matendawa ndi majini osakanizidwa ndi mankhwala, ali ndi cholinga chomaliza chotheka kumaliza thesis kapena pepala lofufuza. Kafufuzidwe ndi kafukufukuyu, komabe, nthawi zambiri zimatenga miyezi kapena zaka, zomwe zimangotenga nthawi yochuluka kwambiri kuti pakhale matenda omwe amafunikira kutsegulira msanga kwamankhwala kudikirira. Chifukwa chake, chithandizo chamankhwala chogwira ntchito nthawi zambiri chimatengera zomwe zidachitika kale, matenda am'munda komanso kuwunika kothandizidwa ndi labotale mwachangu, ndiyeno malangizo othandizira chithandizo amaperekedwa mwachangu.
Mtundu uwu wa chisankho mwamsanga matenda opangidwa mu nthawi yochepa mosavuta chifukwa anthu ambiri amene samvetsa mankhwala, makamaka sangathe molondola ndi mwatsatanetsatane chiweruzo cha matenda tizilombo toyambitsa matenda mabakiteriya zikuchokera sipekitiramu kutenga mankhwala mwakhungu ndi zochokera kulosera, womwenso ndi msewu wofunikira womwe anthu ambiri amayenera kukhumudwa nawo ndikugubuduza asanakhale madokotala otchuka ndikukhala mankhwala abwino.
Chifukwa chake, CPF ndiyokonzeka kusinthanitsa nanu chidziwitso chaukadaulo chokhudzana ndi zamankhwala a Chowona Zanyama, mankhwala a Chowona Zanyama, malamulo azowona zanyama, mfundo, malamulo, msika ndikugwiritsa ntchito, ndi cholinga chokwaniritsa kugawana zidziwitso, kuti olowa m'malo akwere makwerero othandiza m'mwamba kuti aphunzire. chinthu chamtengo wapatali.
Nthawi yotumiza: Aug-17-2022