Pa Seputembara 27, tsamba lovomerezeka la CDE lidawonetsa kuti kugwiritsa ntchito chizindikiro chatsopano cha kirimu cha Pfize Crisaborole (dzina lazamalonda laku China: Sultanming, dzina lamalonda lachingerezi: Eucris a, Staquis) idalandiridwa, mwina kwa ana ndi akulu azaka za 3 miyezi ndi okalamba atopic dermatitis odwala.

Crisaborole ndi molekyu yaing'ono, yopanda mahomoni, yopanda anti-inflammatory topical phosphodiesterase 4 (PDE-4) inhibitor yopangidwa ndi Anacor.Mu Meyi 2016, Pfizer adapeza kampaniyo $ 5.2 biliyoni ndipo adapeza mankhwalawa.Mu Disembala chaka chomwechi, Crisaborole idavomerezedwa ndi FDA kuti igulitse, kukhala mankhwala oyamba aatopic dermatitis ovomerezeka m'zaka 10, komanso mankhwala oyamba akunja akunja oletsa PDE4.

Crisaborole Inhibitors monga mankhwala atsopano, makamaka, mawonekedwe a mlingo wapakamwa akhala akugwiritsidwa ntchito kwa psoriasis yoopsa komanso yoopsa kwambiri ya nyamakazi ya psoriatic, zotsatira zake zazikulu ndizosautsa m'mimba, palibe tsinde lina lapadera.

Crisaborole monga mankhwala apakhungu, otsika pang'ono kudzera pakhungu, kuthekera kwapambuyo kwa vuto la m'mimba kumachepetsedwanso kukhala otsika kwambiri.

Zotsatira zake, Crisaborole mwadzidzidzi inakhala "chiyembekezo cha mudzi wonse" kuyambira zaka 15, madokotala ndi makolo akhala akufunitsitsa kukhala ndi chitetezo, chogwira ntchito komanso chogwiritsira ntchito nthawi yaitali cha mankhwala apakhungu ndi motalika kwambiri.

Kodi mankhwalawa ndi Crisaborole amagwira ntchito bwanji?

Mu 2016, maphunziro awiri a Phase III adabweretsa nkhani zosangalatsa kwambiri, Crisaborole, mafuta odzola a phosphodiesterase-4 (PDE4) inhibitors, kwa odwala atopic dermatitis azaka za 2 (ana ndi akuluakulu), adapeza zotsatira zabwino zachipatala.